The Top 5 Cannabinoids

The Endo-Cannabinoid System

The human body actually produces its own "endogenous" cannabinoids (chemicals otherwise unique to the cannabis plant). These cannabinoids whether formed in your body or produced in the cannabis plant and consumed or applied topically fit neatly into a series of specialized receptors located throughout the human body and skin cells, with their greatest concentration in the hippocampus (which regulates memory), the cerebral cortex (cognition), the cerebellum (motor coordination), the basal ganglia (movement), the hypothalamus (appetite), and the amygdala (emotions). Cannabinoid receptors are similarly found in "every animal species down to the sponge," Dr. Donald Abrams, chief of hematology / oncology at San Francisco General Hospital.

First identified in 1992, the endocannabinoid system (ECS) consists of CB1 receptors predominantly located in the central and peripheral nervous system, connective tissues, gonads, glands, and organs; and CB2 receptors, primarily found in the immune system and also present in the spleen, liver, heart, kidneys, bones, blood vessels, lymph cells, endocrine glands, and reproductive organs. These receptors are produced by the (ECS) and are stimulated and modulated by compounds called endocannabinoids that are produced naturally in the body, like anandamide (ananda is the Sanskrit word for bliss); or by ingesting botanically-based phytocannabinoids rich in Cannabidiol (CBD), the cannabis plant's best known non-psychoactive compound; or by ingesting synthetic cannabinoids produced in a laboratory. After binding to receptors in the body these endo, phyto, and synthetic cannabinoids all produce a wide range of physiological effects, altering everything from blood pressure to pain response to memory retention to appetite and even to mood elevation, but most importantly for its anti inflamatory and neuro-protective qualities , along with stimulating new nerve growth. Although cannabidiol does not directly bind with these receptors, it functions as a mediator, along with naturally occurring terpenes creating the entourage effect to aid in bringing beneficial physiological balance within the body. Think of cannabinoids as a support element along with proper diet, excercise, sleep, relaxation and spiritual well being.

"The endogenous cannabinoid system, named after the plant that led to its discovery, is perhaps the most important physiologic system involved in establishing and maintaining human health," Dr. Dustin Sulak, a leading practitioner of what some have dubbed cannabinopathic medicine, said during a lecture at the 2010 NORML convention. "In each tissue, the cannabinoid system performs different tasks," he said. "But the goal is always the same: homeostasis, the maintenance of a stable internal environment despite fluctuations in the external environment."

Think of the (ECS) system as your body's "core" operating system - a kind of central processing unit that regulates and alters the functioning of every system and keeps them in balance. The (ECS) is the master regulator of all internal systems and is involved in internal processes down to the cellular and nuclear levels. It not only regulates the production of endocannabinoids and their receptors, it manufactures all of the necessary components needed to facilitate and to breakdown and utilize the cannabinoids. Along with regulating our central nervous system as discussed above, it also regulates the endocrine system which regulates all of our glands as well as our blood. Simply put, the Endocannabinoid System is the most important system in our body and Broad Spectrum CBD Rich Hemp Oil is the molecule that brings balance. Take control of your Chemistry!


Terpenes are hydrocarbons that are produced by a wide range of plants. They are aromatic compounds responsible for the pungent odors associated with the hemp plant. Terpenes are what give a rose, lavender, cloves, etc. their distinct smells. Terpenes are used in a wide range of personal care products and scented sprays.

More than 2,000 terpenes exist in nature and the Cannabis Sativa (hemp) plant can produce more than 100 itself.

Terpenes are more than just aromatic compounds though. They are the main building blocks within a plant's physiology that play an important part in the production of plant resins, hormones, vitamins, plant pigments, as well as cannabinoids.

Terpenes comprise 10%-20% of the resin within the trichomes. Trichomes are mushroom shaped heads of resin glands produced by the Cannabis Sativa plant.

Terpenes play an important role in cannabis/hemp medicines. Certain terpenes can regulate how cannabinoids pass through the blood-brain barrier and can alter the rate of production and destruction of serotonin and dopamine neurotransmitters, therefore limiting the movement/availability to cannabinoid receptors.

Terpenes play an incredibly important role by providing us with natural protection from bacteria, fungus, insects, and other environmental stresses.

CBD does not have a direct binding affinity to the receptors in our body. That is why our bodies do not build a resistance to repeated use of Cannabidiol as they do with THC and opiate based medicines which bind directly to specific receptors throughout our bodies. Terpenes allow CBD to bind directly to the CB receptors in our body and skin. They allow CBD to cross the blood brain barrier. They mediate how much or how little crosses that barrier depending on what is needed to create balance and they make CBD more effective at lower doses, hence the entourage effect. This is why it is important to look for a CBD rich Hemp oil product that has a variety of natural occurring terpenes.

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