CBD rich hemp oil and drug interactions

One of the most commonly asked and important questions regarding starting a CBD rich hemp oil regimen is how it will react with other medications?

Let's start with some statistics regarding drug interactions in general. On a yearly average, there are upwards of 100,000 deaths reported from pharmaceutical drug interactions. Over 130 Billion dollars spent on treatment, 2.2 million hospitalized and around 79,000 children hospitalized with complications from drug interactions. As you can see, this problem is huge and concern is of utmost importance.

The goal of supplementing with full spectrum CBD rich hemp oil when taking with other medications is to find the correct therapeutic dose while not interfering with the other medications. Studies have shown that high doses of isolated CBD from a range of 60 mgs and above are most likely to cause an interaction with other medications. Please note that I did say "Isolated CBD". In this blog, we are talking about supplementing with a full spectrum CBD rich hemp oil loaded with naturally occurring terpenes. Okay, what's the difference? Isolated CBD is 1 molecule. Quality, full spectrum CBD rich hemp oil contains other cannabinoids such as Cannabichromene (CBC), Cannabigerol (CBG), Cannabinol (CBN) which have their own therapeutic value, notably as bone stimulators along with naturally occurring terpenes that help CBD cross the blood brain barrier as well as modulating how much or how little crosses that barrier. In addition to that, they are shown to help facilitate the efficient binding of cannabidiol and other cannabinoids to the CB receptors in our brain & body. All of these components work together synergisticly and perform at a higher level with lower doses required. Studies show that typically, low doses of full spectrum CBD rich hemp oil and drug interactions are rare. Full spectrum hemp oil is shown to be far superior than CBD isolate in which higher mg doses are needed, and the therapeutic window is narrower. While there is no specific dosing guidelines with CBD,currently, a general dose is considered 15-30 mgs per day. More in cases of severe pain & discomfort, epilepsy and schizophrenia.

Cannabdiol competes for the same receptor as approximately 60% of prescription medications. The Cytochrome P450 enzyme. A liver enzyme that metabolizes pharmacological substances. There are 2 types of medications in particular to be aware of. One is Warfin, a blood thinner, the other ones are some medications prescribed for epilepsy. If taking these medications, you should advise your doctor as to your intentions if considering taking CBD rich hemp oil products. They may want to monitor your blood levels and possibly lower the dose of your medications.

One strategy to possibly avoid interactions is to take CBD rich hemp oil at a different time than other medications so as not to compete for the same receptor sites. Starting with small doses, taken multiple times a day may also be a good strategy so you can monitor any side effects that may arise before increasing your dose to the optimum level. Since there is not a standard for CBD dosing and the fact that everyone's body chemistry and conditions are different, each individual will have to play around with dosing amounts to find the sweet spot. The goal is to balance the endocannabinoid system and then reduce CBD intake to a maintenance level after 30-90 days. Another approach is to use a full spectrum hemp oil skin balm topically. This method avoids the competition for the P450 Cytokine enzyme in the liver. Our skin has been said to have 5 times more cannabinoid receptors as our organs and has been shown to efficiently absorb substances.

Typically,full spectrum CBD rich hemp oil does not have any side effects other than making you drowsy under higher doses and occasionally a mild headache. Most side effects experienced are said to be from the prescription meds and the fact that cannabidiol has the ability to either amplify or decrease the efficacy of other medications since they compete for the same receptor sites. In some cases such as opiods, this effect can be used to your advantage since the endocannabinoid system works in conjunction with the opioid system to modulate the effects of opioids. It increases the effectiveness of opioids while decreasing respiratory depression. It is shown to decrease tolerance, addictive symptoms and behaviors of opioids. It is also shown to decrease the amount of opioids needed to provide analgesic relief as well as reducing the tolerance to opioids. Cannabidiol works opposite of opioids in that you can reduce the amount of CBD once the endocannabinoid system reaches a balanced state. The benefits of less opiod use is that the side effects associated with their use is greatly reduced or eliminated. Some estimates say that on average, people have reported decreasing their opioid use as much as 75% if not eliminating it all together when including full spectrum hemp oil in their regimen.

Let's recap: when starting a CBD rich hemp oil regimen while on other medications (especially multiple medications) always advise your doctor of your intentions. Start with low doses multiple times a day, rather than one large dose. Or use a topical solution. Monitor for side effects. Increase CBD as needed to achieve desired therapeutic effect. Take at different times than other meds. and to increase efficacy, it is HIGHLY recommended to take a quality Omega 3 supplement. Omega 3's turn into transport molecules that then turn into cannabinoids. Omega 3's work very closely with cannabidiol. In fact, research shows that cannabidiol will not work efficiently without Omega 3's present. Last but not least, do not look at cannabidiol as a cure all. It is just as important to eat healthy organic foods, get proper exercise, ample sleep and a positive attitude towards your health and life in general. Take control of your chemistry and treat your body like the temple that it is. Along with proper diet , exercise and rest, as well as hemp oil supplementation, you can be on your way to a balanced state of inner, and outer well being.

Good health & karma to all

This article was posted on 2018.01.08